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Understanding the Side Effects of GLP-1 Medications and How to Manage Them

GLP-1 medications like Semaglutide (Ozempic) and Tirzepatide (Mounjaro) are powerful weight loss tools, but like all medications, they come with potential side effects. Being informed about what to expect—and how to manage these side effects—can help you stay on track with your weight loss journey.

Common Side Effects

The most frequently reported side effects of GLP-1 medications include:

  • Nausea: This is the most common side effect and usually occurs in the early stages of treatment.
  • Vomiting or Diarrhea: While less common, some patients experience digestive upset as their body adjusts to the medication.
  • Constipation: A slower digestive system can result in constipation for some people.
  • Fatigue: Feeling tired or experiencing low energy is also reported but typically resolves as your body acclimates.

How to Manage Side Effects

For most patients, side effects are mild and temporary, and there are several ways to manage them:

  • Start Slow: Begin with a low dose of Semaglutide or Tirzepatide and gradually increase it over time. This can help your body adjust without overwhelming your system.
  • Stay Hydrated: Drinking plenty of water can help alleviate nausea and prevent dehydration, especially if you’re experiencing vomiting or diarrhea.
  • Eat Small Meals: Eating smaller, more frequent meals that are low in fat can help ease nausea and digestive discomfort.
  • Fiber-Rich Diet: If constipation is an issue, incorporating more fiber into your diet and staying active can help.

Long-Term Management

Most side effects decrease or disappear within a few weeks of starting the medication. However, if symptoms persist, your healthcare provider can adjust your dosage or explore other medications to help manage the side effects.

If you’re using compounded versions of these medications, we can further customize the dosage to minimize side effects while maximizing the weight loss benefits.

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