Starting a new medication can be intimidating, but knowing what to expect during the first few months on GLP-1 medications like Semaglutide (Ozempic) or Tirzepatide (Mounjaro) can help ease the transition. Here’s a breakdown of what most patients experience during the first three months.
Month 1: Adjusting to the Medication
During the first month, your body is adjusting to the medication. You may experience mild side effects like nausea, digestive discomfort, or fatigue as your appetite decreases and your body begins to process food more slowly. These side effects are temporary and typically subside as your body adapts.
At this stage, most patients report a noticeable reduction in hunger and cravings, helping them eat less and make healthier food choices.
Month 2: Noticing Results
By the second month, most patients start seeing significant weight loss and improvements in their energy levels. On average, patients can expect to lose 5-10% of their body weight during the first two months. You’ll also notice that your portion sizes naturally decrease as the medication continues to curb your appetite.
In addition to weight loss, many patients report feeling more energetic and motivated to stay active.
Month 3: Continuing the Journey
By the third month, weight loss becomes even more noticeable. Patients often lose more weight during this period as their body becomes accustomed to smaller portions and a healthier lifestyle. Any initial side effects typically fade by this point, and you’ll feel more confident in managing your new eating habits.
At this stage, regular check-ins with your healthcare provider will help you stay on track, monitor your progress, and make any necessary adjustments to your treatment plan. If you’re using compounded Semaglutide or Tirzepatide, your dosage may be customized based on your progress.
